Indoles and derivatives

Aromatic bicyclic organic compounds that consists of a benzene ring fused to a pyrrole ring with formula: C₈H₇N.

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1,036 – 1,050 of 5,979 results

1,036

Aobchem Ethyl 2-(9-isopropyl-9H-carbazol-3-yl)-2-oxoacetate | 95% | CAS 1892318-69-2 | C19H19NO3 | 500mg

Ethyl 2-(9-isopropyl-9H-carbazol-3-yl)-2-oxoacetate | 95% | CAS 1892318-69-2 | C19H19NO3 | 500mg

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1,037

Ambeed AMBEED

5000892674 13-DIHYDROXY-9H-XANTHEN- 100MG

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1,038

Chemscene CHEMSCENE

5000578407 R-2- 9H-FLUOREN-9-YL METHOX 5G

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1,039

Medchemexpress LLC (2S,4R)-1-((9H-Fluoren-9-yl)methyl) 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate | 122350-59-8 | 97.0% | C21H21NO5 | 25 G

(2S,4R)-1-((9H-Fluoren-9-yl)methyl) 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate is a proline derivative. It targets amino acid derivatives and is classified under the "Others" pathway. Amino acids and their derivatives are recognized for their benefits as ergogenic dietary substances. They can influence the secretion of anabolic hormones, provide fuel during exercise, enhance mental performance during stress-related tasks, and help prevent exercise-induced muscle damage.

Proline derivative
Targets amino acid derivatives
Influences secretion of anabolic hormones
Provides fuel during exercise
Enhances mental performance during stress-related tasks
Helps prevent exercise-induced muscle damage

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1,040

Medchemexpress LLC Indomethacin sodium hydrate | 74252-25-8 | MFCD00227184 | 99.85% | 10 MM * 1 ML in DMSO

Indomethacin sodium hydrate is an orally active and BBB-permeable COX1/2 inhibitor, demonstrating IC50 values of 18 nM for COX-1 and 26 nM for COX-2. It exhibits both anticancer and anti-infective activities, making it suitable for research in cancer, inflammation, and viral infections.

In vitro studies show Indomethacin sodium hydrate (0-150 μM; 24 hours; 3LL-D122 cells) possesses anticancer activity.
It protects host cells from virus-induced damage by activating PKR, which results in eIF2α phosphorylation.
This mechanism leads to the inhibition of viral protein translation and replication, with an IC50 of 2 μM.

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1,041

Aobchem 9 9-Dimethyl-7-(methylthio)-9H-fluorene-2-carboxylic acid | 95% | C17H16O2S | 1g

9 9-Dimethyl-7-(methylthio)-9H-fluorene-2-carboxylic acid | 95% | C17H16O2S | 1g

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1,042

Apexbio Technology LLC Indomethacin(Synonyms: Indocin, Indometacin, Indomethacine, Indocid, Indocine, Amuno, Chrono-Indocid, Elmetacin), 5g, CAS: 53-86-1.

Indomethacin (CAS 53-86-1) is a nonsteroidal anti-inflammatory compound that inhibits cyclooxygenase enzymes Cox-1 and Cox-2 displaying preferential inhibition toward Cox-1 (IC50 230 nM) compared to Cox-2 (IC50 630 nM) Additionally it acts as an agonist of peroxisome proliferator-activated receptor gamma (PPAR ) a transcriptional regulator implicated in adipogenesis Indomethacin can also activate PPAR Furthermore studies indicate that indomethacin stabilizes cholesterol-rich nanoscale clusters enhancing membrane phase separation and potentially altering membrane-dependent signaling pathways This profile makes indomethacin useful for investigating inflammation-associated processes lipid metabolism and membrane signaling mechanisms

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1,043

eMolecules 368866-34-6 | (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-tetrahydropyran-4-yl-propanoic acid | Synthonix | MFCD18252726 | 395.455 | C23H25NO5 | 95.000 | OC(=O)[C@H](CC1CCOCC1)NC(=O)OCC1c2ccccc2-c2ccccc12 | 500mg | 808557217

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-tetrahydropyran-4-yl-propanoic acid | Synthonix | 368866-34-6 | MFCD18252726 | 395.455 | C23H25NO5 | 95.000 | OC(=O)[C@H](CC1CCOCC1)NC(=O)OCC1c2ccccc2-c2ccccc12 | 500mg | 808557217

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1,044

eMolecules 252049-16-4 | (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(3-methylimidazol-4-yl)propanoic acid | Combi-Blocks, Inc. | MFCD02259494 | 391.427 | C22H21N3O4 | 96.000 | Cn1cncc1C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 1g | 603136903

(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(3-methylimidazol-4-yl)propanoic acid | Combi-Blocks, Inc. | 252049-16-4 | MFCD02259494 | 391.427 | C22H21N3O4 | 96.000 | Cn1cncc1C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 1g | 603136903

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1,045

eMolecules 251316-98-0 | (2S,3R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methyl-pentanoic acid | Pharmablock | MFCD01631976 | 353.418 | C21H23NO4 | 97.000 | CC[C@@H](C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 2.5g | 840559086

(2S,3R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methyl-pentanoic acid | Pharmablock | 251316-98-0 | MFCD01631976 | 353.418 | C21H23NO4 | 97.000 | CC[C@@H](C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 2.5g | 840559086

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1,046

Cayman Chemical IndomethacIn 1g

A non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively); reduces filter paper-disc induced growth of granulation tissue in chick chorioallantoic membranes; reduces ocular inflammation induced by bovine serum in rabbits; reduces paw edema in a rat model of carrageenan-induced inflammation

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1,047

eMolecules 105047-45-8 | (2S)-6-amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid | Synthonix | MFCD00038539 | 368.433 | C21H24N2O4 | 97.000 | NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 1g | 571833005

(2S)-6-amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid | Synthonix | 105047-45-8 | MFCD00038539 | 368.433 | C21H24N2O4 | 97.000 | NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 1g | 571833005

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1,048

eMolecules 2S-2-9H-FLUOREN-9-YL 1G

5000215957 2S-2-9H-FLUOREN-9-YL 1G

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1,049

eMolecules 2S-2-CYCLOPROPYL-2-9H-FL 1G

5000188447 2S-2-CYCLOPROPYL-2-9H-FL 1G

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1,050

eMolecules 2S 4R-1-9H-FLUOREN-9-Y 1G

5000188652 2S 4R-1-9H-FLUOREN-9-Y 1G

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Indoles and derivatives

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Medchemexpress LLC (2S,4R)-1-((9H-Fluoren-9-yl)methyl) 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate | 122350-59-8 | 97.0% | C21H21NO5 | 25 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Indomethacin sodium hydrate | 74252-25-8 | MFCD00227184 | 99.85% | 10 MM * 1 ML in DMSO Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (2S,4R)-1-((9H-Fluoren-9-yl)methyl) 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate | 122350-59-8 | 97.0% | C21H21NO5 | 25 G

Medchemexpress LLC Indomethacin sodium hydrate | 74252-25-8 | MFCD00227184 | 99.85% | 10 MM * 1 ML in DMSO